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IPREG NT

IPREG NT 75 mg/10 mg Tablet is a combination medicine used for the treatment of neuropathic pain.

This medicine decreases the pain by stopping the movement of pain signals to the brain.

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Pregabalin (75mg) + Nortriptyline (10mg)

IPREG NT 75 mg/10 mg Tablet is a combination of two medicines: Pregabalin and Nortriptyline. 

Pregabalin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. 

Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).

SIDE EFFECTS OF IPREG NT TABLET

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine.

 Consult your doctor if they persist or if you’re worried about them

Common side effects of IPREG NT

  • Dryness in mouth
  • Increased heart rate
  • Increased appetite
  • Increased libido
  • Paresthesia (tingling or pricking sensation)
  • Vertigo
  • Vomiting
  • Nausea
  • Erectile dysfunction
  • Joint pain
  • Constipation
  • Difficulty in urination
  • Weight gain
  • Sleepiness
  • Dizziness
  • Tiredness
  • Blurred vision
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Uncoordinated body movements

SAFETY ADVICE

Alcohol: IPREG NT 75 mg/10 mg Tablet may cause excessive drowsiness with alcohol.

Pregnancy: IPREG NT 75 mg/10 mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding: IPREG NT 75 mg/10 mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breast milk and harm the baby.

Driving: IPREG NT 75 mg/10 mg Tablet may cause side effects which could affect your ability to drive.
As IPREG NT 75 mg/10 mg Tablet may affect your alertness which may affect your ability to drive.

Kidney: IPREG NT 75 mg/10 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of IPREG NT 75 mg/10 mg Tablet may be needed. Please consult your doctor.

Liver: IPREG NT 75 mg/10 mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of IPREG NT 75 mg/10 mg Tablet may not be needed in these patients. Please consult your doctor.